James M Wilson Selected Research

Hemophilia A (Haemophilia)

1/2022	Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A.
1/2019	CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX-knockout mice.
7/2018	Optimized Adeno-Associated Viral-Mediated Human Factor VIII Gene Therapy in Cynomolgus Macaques.
1/2017	Characterization of Adeno-Associated Viral Vector-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice.
2/2004	Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

James M Wilson Research Topics

Disease

23	Infections 12/2021 - 12/2004
12	Neoplasms (Cancer) 11/2018 - 03/2002
11	Myocardial Infarction 07/2020 - 03/2004
9	Homozygous Familial Hypercholesterolemia 09/2021 - 03/2005
9	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 07/2003
9	Atrial Fibrillation 07/2013 - 03/2004
9	Stroke (Strokes) 07/2013 - 03/2004
8	Ornithine Carbamoyltransferase Deficiency Disease 03/2022 - 01/2002
8	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2022 - 02/2013
8	Atherosclerosis 11/2013 - 06/2004
6	Hypercholesterolemia 01/2021 - 06/2004
6	Mucopolysaccharidosis I (Hurler Syndrome) 01/2019 - 10/2014
6	Coronary Artery Disease (Coronary Atherosclerosis) 04/2015 - 07/2008
6	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 08/2014 - 06/2004
6	Renal Insufficiency (Renal Failure) 07/2013 - 06/2008
5	Hemophilia A (Haemophilia) 01/2022 - 02/2004
4	Central Nervous System Diseases (CNS Diseases) 01/2021 - 11/2016
4	Inflammation (Inflammations) 01/2020 - 10/2004
4	Human Influenza (Influenza) 11/2018 - 09/2007
4	Thrombosis (Thrombus) 01/2011 - 06/2008
4	Heart Failure 04/2010 - 08/2002
4	Vesicular Stomatitis 01/2010 - 09/2002
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2010 - 05/2005
3	Severe Acute Respiratory Syndrome 01/2022 - 05/2006
3	Hypertension (High Blood Pressure) 01/2021 - 06/2008
3	Inborn Urea Cycle Disorders 01/2020 - 02/2012
3	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 08/2015
3	Malaria 12/2015 - 03/2002
3	ST Elevation Myocardial Infarction 07/2014 - 04/2010
3	Acute Coronary Syndrome 11/2013 - 10/2009
3	Blindness (Hysterical Blindness) 01/2013 - 04/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 10/2018
2	Hemorrhage 01/2022 - 07/2018
2	Liver Diseases (Liver Disease) 01/2019 - 02/2012
2	Breast Neoplasms (Breast Cancer) 11/2018 - 03/2013
2	Coma (Comas) 11/2018 - 01/2017
2	Hyperammonemia 11/2018 - 03/2016
2	Crigler-Najjar Syndrome 09/2018 - 01/2018
2	Mucopolysaccharidosis II (Hunter Syndrome) 09/2018 - 11/2016
2	Choroidal Neovascularization 01/2018 - 04/2005
2	Viremia 01/2018 - 10/2013
2	Hypoxia (Hypoxemia) 09/2017 - 01/2016
2	Ebola Hemorrhagic Fever 12/2016 - 11/2007
2	Neoplasm Metastasis (Metastasis) 09/2016 - 02/2004
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2016 - 06/2014
2	Hemophilia B (Haemophilia B) 12/2015 - 04/2005
2	Cystic Fibrosis (Mucoviscidosis) 09/2015 - 03/2009
2	Metabolic Diseases (Metabolic Disease) 06/2015 - 05/2013
2	Pneumonia (Pneumonitis) 09/2013 - 07/2007
2	Sepsis (Septicemia) 09/2013 - 08/2012
2	Wound Infection (Wound Infections) 09/2013 - 07/2013
2	Respiratory Insufficiency (Respiratory Failure) 07/2013 - 01/2011

Drug/Important Bio-Agent (IBA)

15	VaccinesIBA 01/2022 - 03/2002
14	LDL Receptors (LDL Receptor)IBA 01/2021 - 06/2004
11	EnzymesIBA 09/2021 - 02/2012
9	AntigensIBA 01/2022 - 03/2002
9	Proteins (Proteins, Gene)FDA Link 10/2020 - 08/2002
8	Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)IBA 03/2022 - 09/2003
6	Iduronidase (alpha-L-Iduronidase)IBA 01/2019 - 10/2014
6	AntibodiesIBA 01/2019 - 11/2011
6	DNA (Deoxyribonucleic Acid)IBA 03/2016 - 08/2005
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2015 - 03/2008
4	Factor VIII (Coagulation Factor VIII)IBA 01/2022 - 02/2004
4	Therapeutic UsesIBA 09/2021 - 01/2019
4	Urea (Carbamide)FDA LinkGeneric 11/2018 - 01/2002
4	Biomarkers (Surrogate Marker)IBA 10/2017 - 03/2013
4	CholesterolIBA 08/2014 - 05/2005
4	Glycoproteins (Glycoprotein)IBA 01/2010 - 05/2002
4	LipidsIBA 12/2008 - 06/2004
3	Pharmaceutical PreparationsIBA 01/2022 - 02/2007
3	Monoclonal AntibodiesIBA 12/2021 - 05/2013
3	LigandsIBA 01/2019 - 02/2003
3	EpitopesIBA 11/2018 - 04/2005
3	Neutralizing AntibodiesIBA 05/2016 - 05/2006
3	Broadly Neutralizing AntibodiesIBA 01/2016 - 10/2013
3	Retinaldehyde (Retinal)IBA 01/2013 - 07/2003
3	Adenovirus VaccinesIBA 07/2007 - 10/2005
3	Erythropoietin FDA Link 05/2004 - 08/2002
2	Codon (Codons)IBA 09/2021 - 01/2017
2	Uridine Diphosphate (UDP)IBA 09/2018 - 01/2018
2	BilirubinIBA 09/2018 - 01/2018
2	TransferasesIBA 09/2018 - 01/2018
2	Transaminases (Aminotransferases)IBA 01/2018 - 01/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 04/2005
2	SpermineIBA 10/2017 - 09/2005
2	GlycosaminoglycansIBA 02/2016 - 10/2014
2	Liposomes (Liposome)IBA 09/2015 - 09/2005
2	hydrogen sulfite (bisulfite)IBA 11/2013 - 06/2012

Therapy/Procedure

28	Therapeutics 11/2020 - 08/2002
14	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 04/2015 - 03/2004
9	Percutaneous Coronary Intervention 04/2015 - 06/2008
5	Stents 07/2020 - 06/2008
4	Radiotherapy 06/2021 - 06/2014
4	Transplantation 06/2015 - 01/2005
4	Length of Stay 07/2013 - 03/2004
2	Intravenous Injections 11/2018 - 08/2006
2	Liver Transplantation 01/2017 - 08/2009
2	Enzyme Replacement Therapy 11/2016 - 12/2014
2	Castration 09/2016 - 08/2015
2	Chemoradiotherapy 01/2016 - 06/2014